WebMay 17, 2024 · FGF23 is a hormone secreted mainly by osteocytes and osteoblasts in bone. Its pivotal role concerns the maintenance of mineral ion homeostasis. It has been confirmed that phosphate and vitamin D metabolisms are related to the effect of FGF23 and its excess or deficiency leads to various hereditary diseases. WebMay 18, 2024 · FGF23 is a hormone secreted mainly by osteocytes and osteoblasts in bone. Its pivotal role concerns the maintenance of mineral ion homeostasis. It has been confirmed that phosphate and vitamin D metabolisms are related to the effect of FGF23 and its excess or deficiency leads to various hereditary diseases.
The FGF family: biology, pathophysiology and therapy - PMC
WebThe involvement of FGF signalling in human disease is well documented. Deregulated … WebMay 1, 2024 · Fibroblast growth factor 21 (FGF21), a member of the endocrine FGF … tn3 blanche bleu
Basic Fibroblast Growth Factor - an overview - ScienceDirect
WebApr 12, 2024 · FGF23 is a bone-derived phosphaturic through its action at the proximal tubules and thus, it is correlated with phosphate excretion per nephron [ 3 ]. FGF23 rises during CKD progression as early as stage 2, a long time before the increase in serum phosphate levels, which emerge at stage 4 or later. WebFeb 15, 2024 · Several FGF ligands and receptors are expressed in the gastrointestinal tract during development and in adult tissue. Table 1. FGF Ligands in Human and Their Orthologs in Mouse and Zebrafish All four FGF receptors are expressed in the intestine. WebSep 2, 2024 · Summary of the main roles of FGF/FGFR signaling in organ development, metabolism, and disease. FGF/FGFR signaling participates in the development of almost all organ such as lung, heart, urinary ... tn3dry cask storage