Webb21 mars 2024 · This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the … WebbPRK13362 (PSSM ID: 184001): Conserved Protein Domain Family PRK13362, protoheme IX farnesyltransferase; Provisional
ctaB - Protoheme IX farnesyltransferase - Wolbachia …
WebbCatalysis of the reaction: protoheme IX + (2E,6E)-farnesyl diphosphate + H2O = heme O + diphosphate. Synonyms. haem O synthase activity, heme A:farnesyltransferase activity, … WebbAs part of a recent genome wide association study (GWAS) to identify novel loci that alter the expression of cytolytic toxins, a polymorphism in the cyoE gene, which encodes a protoheme IX farnesyltransferase, was identified. This enzyme is essential for processing heme into the electron transport chain for use as an electron acceptor. myrna lee inc
Frontiers Absence of Protoheme IX Farnesyltransferase CtaB …
Protoheme IX farnesyltransferase, mitochondrial is an enzyme that in humans is encoded by the COX10 gene. Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric … Visa mer The COX10 gene is located on the p arm of chromosome 17 in position 12 and spans 139,277 base pairs. The gene produces a 48.9 kDa protein composed of 443 amino acids. This gene has an unusually long 3' untranslated region measuring … Visa mer Mutations in the COX10 gene can result in numerous clinical phenotypes, from tubulopathy and leukodystrophy to Leigh syndrome to fatal infantile cardiomyopathy to a French Canadian … Visa mer This protein interacts with FAM136A. Visa mer • Pitceathly RD, Taanman JW, Rahman S, Meunier B, Sadowski M, Cirak S, et al. (December 2013). "COX10 mutations resulting in complex multisystem mitochondrial disease that remains stable into adulthood" Visa mer The protein encoded by COX10 is an assembly factor essential to COX synthesis, participating in the first step of the mitochondrial heme A biosynthetic pathway. It catalyzes the farnesylation of the vinyl group at position C2 of protoheme ( Visa mer • Human COX10 genome location and COX10 gene details page in the UCSC Genome Browser. Visa mer Webb1 maj 2000 · This gene encodes heme A:farnesyltransferase, which catalyzes the first step in the conversion of protoheme to the heme A prosthetic groups of the enzyme. All three nuclear genes now linked to isolated COX deficiency are involved in the maturation and assembly of COX, emphasizing the major role of such genes in COX pathology. Webbprotoheme M to heme 0 in the cytoplasmic membranes, and 4) a binding motif for allylic polyprenyl diphosphate is conserved in a cytoplasmic loop of the CyoE protein family (11). Based on these observations, we have postulated that the cyoE gene en- codes a novel enzyme, protoheme M farnesyltransferase (heme 0 synthase). the song adidas