WebMar 17, 2024 · The World Health Organization published its first catalogue of mutations in M. tuberculosis known to be associated with resistance to a range of antibiotics in June 2024. This paper, just published in Lancet Microbe, describes in detail how the catalogue was constructed and its effectiveness, as measured by sensitivity and specificity.The … WebFeb 24, 2024 · The CRyPTIC Consortium. European Respiratory Journal 2024; DOI: 10.1183/13993003.00239-2024 . Article; Info & Metrics; PDF; Abstract. Drug susceptibility testing of M. tuberculosis is rooted in a binary susceptible/resistant paradigm. Whilst there are considerable advantages in measuring the minimum inhibitory concentrations (MICs) …
The Coming of Age of Drug-Susceptibility Testing for …
WebDec 2, 2024 · We incorporate mutation catalogues from the CRyPTIC consortium et al. (2024) and from Walker et al. (2015), and make improvements based on performance on an initial set of 3206 and an independent set of 5845 M. tuberculosis Illumina sequences. Web5 hours ago · Neetu Kapoor was in the eye of a storm recently after one of her Instagram stories was seen as a jibe on Katrina Kaif.Katrina and Ranbir Kapoor were in a long-term … highlight mu vs city
New publication: WHO catalogue of M. tuberculosis resistance ... - CRyPTIC
WebFeb 3, 2024 · The CRyPTIC consortium has collected 20,637 clinical tuberculosis samples worldwide. The layout and concentrations of the anti-TB drugs on the (A) UKMYC6 and (B) UKMYC5 microdilution 96-well plates. All concentrations are in mg/L and for clarity only the first and last concentration in each doubling series are given. WebJun 17, 2024 · The CRyPTIC Consortium and the 100,000 Genomes Project. Prediction of susceptibility to first-line tuberculosis drugs by DNA sequencing. N. Engl. J. Med. 379, 1403–1415 (2024). WebAug 16, 2024 · The CRyPTIC consortium has shown that whole-genome sequencing can be used to predict susceptibility to the first-line tuberculosis drugs. 6. The CRyPTIC Consortium 100,000 Genomes Project Prediction of susceptibility to first-line tuberculosis drugs by DNA sequencing. N Engl J Med. 2024; 379: 1403-1415. Crossref; small outdoor sheds clearance